論文
公開件数:60件
No. 発表論文の標題 著者名等 掲載誌名 巻/号,頁 出版年月 ISSN DOI URL
1 『心筋細胞フィジオーム理解のための電子教科書“e-Heart”』の生理学教育教材および研究資材としての活用に向けて 第5回ヒト心室細胞(HuVEC)モデルの刺激頻度依存性
姫野友紀子、天野晃、野間昭典
日本生理学会雑誌
80/ 4, 85-91
2018/10



2 A new myofilament contraction model with ATP consumption for ventricular cell model
Yuttamol Muangkram, Akinori Noma, Akira Amano
The Journal of Physiological Sciences
68/ 5, 541-554
2018/09

10.1007/s12576-017-0560-x

3 『心筋細胞フィジオーム理解のための電子教科書“e-Heart”』の生理学教育教材および研究資材としての活用に向けて 第4回ヒト心室細胞(HuVEC)モデルのCa2+誘発Ca2+放出(CICR)
姫野友紀子、天野晃、野間昭典
日本生理学雑誌
80/ 3, 58-70
2018/07



4 『心筋細胞フィジオーム理解のための電子教科書“e-Heart”』の 生理学教育教材および研究資材としての活用に向けて 第3 回 ヒト心室筋細胞(HuVEC)モデルのCa2+ 動態と 遅延後脱分極(DAD)の発生
姫野友紀子、天野晃、野間昭典
日本生理学雑誌
80/ 2, 26-39
2018/04



5 『心筋細胞フィジオーム理解のための電子教科書“e-Heart”』の 生理学教育教材および研究資材としての活用に向けて 第 2 回 ヒト心室筋細胞(HuVEC)モデルを用いた 早期後脱分極(EAD)の再現
姫野友紀子,天野 晃,野間 昭典
日本生理学雑誌
80/ 1, 3-10
2018/01



6 『心筋細胞フィジオーム理解のための電子教科書“e-Heart”』の生理学教育教材および研究資材としての活用に向けて第1 回 Visual Studio を用いた包括的ヒト心室筋細胞モデルの実行
姫野友紀子、天野晃、野間昭典
日本生理学雑誌
79/ 4, 64-72
2017/11



7 Regulation of the glucose supply from capillary to tissue examined by developing a capillary model
Maeda A, Himeno Y, Ikebuchi M, Noma A, Amano A
J Physiol Sci.
68/ 4, 355-367
2017/04

10.1007/s12576-017-0538-8.

8 Mechanisms underlying the volume regulation of the interstitial fluid by capillaries: a simulation study
Yukiko Himeno, Masayuki Ikebuchi, Akitoshi Maeda, Akinori Noma, Akira Amano
Integrative Medicine Research
5/ 1, 11-21
2016/01



9 Modeling analysis of inositol 1,4,5-trisphosphate receptor-mediated Ca mobilization under the control of glucagon-like peptide-1 in mouse pancreatic b-cells.
Himeno Y. Asakura K, Cha CY, Memida H., Powell T, Amano A、Noma A
Am J Physiol Cell Physiol
310/ 5, C337-47
2015/11



10 A human ventricular myocyte model with refined representation of excitation-contraction coupling
Y. Himeno, K. Asakura, C. Y. Cha, H. Memida, T. Powell, A. Amano, A. Noma
Biophys. J
109/ 2, 415-427
2015/07



11 心臓ペースメーカー細胞のイオン機序について
姫野友紀子,天野晃,野間昭典
循環器専門医
23/ 1, 9-17
2015/03



12 EAD and DAD mechanisms analyzed by developing a new human ventricular cell model
K. Asakura, C. Cha, H. Yamaoka, Y. Horikawa, H. Memida, T. Powell, A. Amano, A. Noma
Progress in Biophysics and Molecular Biology
116/ 1, 11-24
2014/09



13 Steady-state solutions of cell volume in a cardiac myocyte model elaborated for membrane excitation, ion homeostasis and Ca2+ dynamics.
Cha CY, Noma A.
J Theor Biol
307, 70-81
2012



14 Systems Analysis of GLP-1 Receptor Signaling in Pancreatic β-cells.
Takeda Y, Amano A, Noma A, Nakamura Y, Fujimoto S, Inagaki N,
Am J Physiol Cell Physiol.
138/ 1, 39-47
2011



15 Minor Contribution of Cytosolic Ca2+ Transients to the PacemakerRhythm in Guinea Pig Sinoatrial Node Cells.
Himeno Y, Toyoda F, Satoh H, Amano A, Cha CY, Matsuura H, Noma A:
Am J Physiol Heart Circ Physiol,
300/ 1, H251-61
2011



16 Analyzing electrical activities of pancreatic β cells using mathematical models,
Cha CY, Powell T, Noma A,
Prog Biophys Mol Biol.
107/ 2, 265-73
2011/11



17 Time-dependent changes in membrane excitability during glucose-induced bursting activity in pancreatic β cells,
Cha CY, Santos E, Amano A, Shimayoshi T, Noma A,
J Gen Physiol
138/ 1, 39-47
2011/07



18 Ionic mechanisms and Ca2+ dynamics underlying the glucose response of pancreatic β cells: a simulation study,
Cha CY, Nakamura Y, Himeno Y, Wang J, Fujimoto S, Inagaki N, Earm YE, Noma A,
J Gen Physiol
138/ 1, 21-37
2011/07



19 Reply to "Letter to the Editor: 'Validating the requirement for beat-to-beat coupling of the Ca2+ clock and M clock in pacemaker cell normal automaticity'"
Himeno Y, Toyoda F, Matsuura H, Noma A
Am J Physiol Heart Circ Physiol
300/ 6, H2325-H2326
2011/04



20 Magnesium gating of cardiac gap junction channels
Matsuda H, Kurata Y, Oka C, Matsuoka S, Noma A.
Prog Biophys Mol Biol
103/ 1, 102-110
2010



21 Characterization of the cardiac Na+/K+ pump by development of a comprehensive and mechanistic model
Oka C1, Cha CY1, Noma A
J Theor Biol
256/ 1, 68-77
2010



22 Characterization of the cardiac Na+/K+ pump by development of a comprehensive and mechanistic model
Oka C1, Cha CY1, Noma A
J Theor Biol
265/ 1, 68-77
2010



23 A, Minor contribution of cytosolic Ca2+ transients to the pacemaker rhythm in guinea pig sinoatrial node cells,
Himeno Y, Toyoda F, Satoh H, Amano A, Cha CY, Matsuura H, Noma A
Am J Physiol Heart Circ Physiol.
300, H251-61
2010/10



24 Modeling the cardiac Na+/H+ exchanger based on major experimental findings,
Cha CY and Noma A,
Mol Cells.

2009



25 Development of a model of the Na+/H+ exchanger and its central role in regulation of intracellular pH and Na+ in cardiac myocytes,
Cha CY, Oka C, Earm YE, Wakayabashi S and Noma A,
Biophys J.

2009



26 A Novel Method to Quantify Contribution of Channels and Transporters to Membrane Potential Dynamics,
Cha CY, Himeno Y, Shimayoshi T, Amano A and Noma A
Biophys J.

2009



27 Modeling the cardiac Na+/H+ exchanger based on major experimental findings, Mol Cells.
Cha CY and Noma A
Mol Cells.
28/ (2),, p81-5
2009



28 A Novel Method to Quantify Contribution of Channels and Transporters to Membrane Potential Dynamics
Cha CY, Himeno Y, Shimayoshi T, Amano A and Noma A
Biophys J.
97/ 12, 3086-94
2009



29 Development of a model of the Na+/H+ exchanger and its central role in regulation of intracellular pH and Na+ in cardiac myocytes
Cha CY, Oka C, Earm YE, Wakayabashi S and Noma A
Biophys J.
97/ 10, 2674-83
2009



30 Ionic mechanisms underlying the positive chronotropy induced by beta1-adrenergic stimulation in guinea pig sinoatrial node cells: s simulation study
Himeno Y, Sarai N. Matsuoka S & Noma A
J Physiol Sci
58, 53-65
2008



31 A simulation study on the activation of cardiac CaMKII delta-isoform and its regulation by phosphatases
Chiba H, Schneider NS, Matsuoka S, Noma A
Biophys J
95, 2139-49
2008



32 A new integrated method for analyzing heart mechanics using a cell-hemodynamics -autonomic nerve control coupled model of the cardiovascular system
Kuzumoto et al
Prog Biophys Mol Biol
96/ 1-3, 44-59
2008



33 A simulation study on the activation of cardiac CaMKII delta-isoform and its regulation by phosphatases
Chiba H, Schneider NS, Matsuoka S, Noma A
Biophys J
95, 2139-49
2008



34 Ionic mechanisms underlying the positive chronotropy induced by beta1-adrenergic stimulation in guinea pig sinoatrial node cells: s simulation study
Himeno Y, Sarai N. Matsuoka S & Noma A
J Physiol Sci
58, 53-65
2008



35 心筋細胞のシミュレーションとその応用、
野間昭典、姫野友紀子、車采映、
月刊 bioindustry

2008/12



36 Simulation analysis of intracellular Na+ and Cl- homeostasis during beta 1-adrenergic stimulation of cardiac myocyte
Kuzumoto, Takeuchi, Nakai, Oka , Noma & Matsuoka
Prog.Biophys Mol Biol
96, 171-186
2007



37 The Cross-Bridge Dynamics during Ventricular Contraction Predicted by Coupling the Cardiac Cell Model with a Circulation Model
Shim EB, Amano A, Takahata T, Shimayoshi T, Noma A
J Physiol Sci
57, 275-285
2007



38 Resistance of Cardiac Cells to NCX Knockout: A Model Study
Noble D, Sarai N, Noble PJ, Kobayashi T, Matsuoka S, Noma A
Annals of the New York Academy of Sciences
1099, 306-309
2007



39 Role of Ca2+ transporters and channels in the cardiac cell volume regulation
akeuchi A, Tatsumi S, Sarai N, Terashima K, Matsuoka S, Noma A
Annals of the New York Academy of Sciences
1099, 377-382
2007



40 Ionic mechanisms of cardiac cell swelling induced by blocking Na+/K+ pump as revealed by experiments and simulation
Takeuchi A, Tatsumi S, Sarai N, Terashima K, Matsuoka S and Noma A
J Gen Physiol
128, 495-507
2007



41 Ionic mechanisms of cardiac cell swelling induced by blocking Na+/K+ pump as revealed by experiments and simulation
Takeuchi A, Tatsumi S, Sarai N, Terashima K, Matsuoka S and Noma A
J Gen Physiol
128, 495-507
2007



42 Role of Ca2+ transporters and channels in the cardiac cell volume regulation
Takeuchi A, Tatsumi S, Sarai N, Terashima K, Matsuoka S, Noma A
Annals of the New York Academy of Sciences
1099, 377-382
2007



43 Resistance of Cardiac Cells to NCX Knockout: A Model Study
Noble D, Sarai N, Noble PJ, Kobayashi T, Matsuoka S, Noma A
Annals of the New York Academy of Sciences
1099, 306-309
2007



44 The Cross-Bridge Dynamics during Ventricular Contraction Predicted by Coupling the Cardiac Cell Model with a Circulation Model
Shim EB, Amano A, Takahata T, Shimayoshi T, Noma A
J Physiol Sci
57, 275-285
2007



45 Simulation analysis of intracellular Na+ and Cl- homeostasis during beta 1-adrenergic stimulation of cardiac myocyte
Kuzumoto, Takeuchi, Nakai, Oka , Noma & Matsuoka
Prog.Biophys Mol Biol
96, 171-186
2007



46 simBio: A java package for the development of detailed cell models
Sarai N, Matsuoka S, Noma A
Prog Biophys Mol Biol
90, 360-377
2006



47 Modeling the Ca2+ gate on cardiac gap junction channel
Oka C, Matsuda H, Sarai N, Noma A
J.Physiol.Sci
56, 79-85
2006



48 Calcium-mediated coupling between mitochondrial substrate dehydrogenation and cardiac workload in single guinea-pig ventricular myocytes
Jo H, Noma A, Matsuoka S
Journal of Molecular and Cellular Cardiology
40, 394-404
2006



49 Modelling Cl- homeostasis and volume regulation of the cardiac cell
Terashima K, Takeuchi A, Sarai N, Matsuoka S, Shim EB, Leem CH and Noma A
Philos Transact A Math Phys Eng Sci
364, 1245-1265
2006



50 A Simulation Study to Rescue the Na+/Ca2+ Exchanger Knockout Mice
Nobuaki Sarai, Tsutomu Kobayashi, Satoshi Matsuoka and Akinori Noma
The Journal of Physiological Sciences
56, 211-217
2006



51 The Cl- homeostasis and volume regulation of the cardiac cell model
Terashima K, Takeuchi A, Sarai N, Matsuoka S, Shim EB, Leem CH and Noma A
Philos Transact A Math. Phys. Eng. Sci
364/ 1-3, 1245-1265
2006



52 Regulation of oxidative phosphorylation in intact mammalian heart in vivo
Korzeniewski B, Noma A, Matsuoka S
Biophysical Chemistry
116, 145-157
2005



53 創薬研究における細胞機能シミュレーション
松岡達,野間昭典
月刊薬事
46, 1257-1264
2004



54 細胞・生体機能シミュレーションプロジェクト‐数理時空間に生体活動を実現す
野間昭典,松田哲也,松岡達,皿井伸明
現代医療
36, 1073-1079
2004



55 細胞・生体機能シミュレーションプロジェクト
天野晃,松田哲也,野間昭典
ヒューマンインタフェース学会誌
6, 39-44
2004



56 Two types of spontaneous depolarizations in the interstitial cells freshly prepared from the murine small intestine.
Goto K, Matsuoka S, Noma A
J Physiol.
55, 411-422
2004



57 simBio:生物学的ダイナミックモデル開発基盤
皿井伸明,野間昭典
日本エム・イー学会雑誌(BME)
3, 11
2004



58 Simulation of ATP Metabolism in Cardiac Excitation-Contraction Coupling
Matsuoka S., Sarai N., Jo H. and Noma A
Progress in Biophysics and Molecular Biology
85, 279-299
2004



59 Two types of spontaneous depolarizations in the interstitial cells freshly prepared from the murine small intestine
K Goto, S Matsuoka, A Noma
Journal of Physiology
599, 411-422
2004



60 An in silico study of energy metabolism in cardiac excitation-contraction coupling
Matsuoka S, Jo H, Sarai N, Noma A
Japanese Journal of Physiology
54, 517-522
2004