論文
公開件数:100件
No. 発表論文の標題 著者名等 掲載誌名 巻/号,頁 出版年月 ISSN DOI URL
1 毒か?栄養素か? 必須微量元素セレンの生物学
三原久明
海洋科学研究
31/ 2, 95-100
2018/11



2 Delivery of selenium to selenophosphate synthetase for selenoprotein biosynthesis
Tobe, R., Mihara, H.
Biochim Biophys Acta
1862/ 11, 2433-2440
2018/06



3 Characterization of a Novel Porin-Like Protein, ExtI, from Geobacter sulfurreducens and Its Implication in the Reduction of Selenite and Tellurite
Jahan, M. I. Tobe, R. Mihara, H.
Int J Mol Sci
19/ 3, 809
2018/03

10.3390/ijms19030809

4 Identification of selenomethionine, selenocysteine, and Se-methylselenocysteine in the selenium-enriched common ice plant
Tobe, R.; Koga, H.; Tani, Y.; Tajima, H.; Tsuji, A.; Mihara, H.
Biomed. Res. Trace Elem.
28/ 3, 135-142
2017



5 Selective fluorescence detection method for selenide and selenol using monochlorobimane
Imai, T.; Kurihara, T.; Esaki, N.; Mihara, H.
Anal Biochem
532, 1-8
2017/09



6 鉄硫黄クラスターおよびセレンタンパク質生合成とその分子機構
戸部隆太, 三原久明
硫酸と工業
70/ 2, 23-28
2017/02



7 Relationship between the synthesis of glycosphingolipids and phospholipids and mycelial growth in Neurospora crassa
Tobe, R., Tani, Y., Kataoka, M., Yamashita, Y., and Mihara, H.
Trace Nutr. Res.
33, 13-20
2016/12



8 A non-radioactive assay for selenophosphate synthetase activity using recombinant pyruvate pyrophosphate dikinase from Thermus thermophilus HB8
Kamada, S., Okugochi, T., Asano, K., Tobe, R., Mihara, H., Nemoto, M., Inagaki, K., and Tamura, T.
Biosci. Biotechnol. Biochem.
80/ 10, 1970-1972
2016/10



9 Purification and properties of 4-methyl-5-hydroxyethylthiazole kinase from Escherichia coli
Tani, Y., Kimura, K., and Mihara, H.
Biosci. Biotechnol. Biochem.
80/ 3, 514-517
2016/03



10 Purification and properties of glycine oxidase from Pseudomonas putida KT2440
Equar, M. Y., Tani, Y., and Mihara, H.
J. Nutr. Sci. Vitaminol.
61, 506-510
2015



11 Functional expression of L-lysine alpha-oxidase from Scomber japonicus in Escherichia coli for one-pot synthesis of L-pipecolic acid from DL-lysine
Tani, Y., Miyake, R., Yukami, R., Dekishima, Y., China, H., Saito, S., Kawabata, H., and Mihara, H.
Appl. Microbiol. Biotechnol.
99, 5045-5054
2015



12 Heterologous expression of L-lysine alpha-oxidase from Scomber japonicus in Pichia pastoris and functional characterization of the recombinant enzyme
Tani, Y., Omatsu, K., Saito, S., Miyake, R., Kawabata, H., Ueda, M., Mihara, H.
J Biochem
157, 201-210
2015



13 L-ピペコリン酸およびL-プロリンの生成に関わる多機能性酵素
三原久明
生化学
87, 326-332
2015/03



14 Effects of sugars and salt on the production of glycosphingolipids in Mariannaea elegans
Tani, Y., Yamashita, Y., Saito, S., and Mihara, H.
Trace Nutr. Res.
31, 37-44
2014



15 Glutathione Contributes to the Efflux of Selenium from Hepatoma Cells
Imai, T., Kurihara, T., Esaki, N., Mihara, H.
Biosci. Biotechnol. Biochem.
78/ 8, 1376-1780
2014/08



16 Characterization of a thermostable 2, 4-diaminopentanoate dehydrogenase from Fervidobacterium nodosum Rt17-B1
Fukuyama, S. Mihara, H. Miyake, R. Ueda, M. Esaki, N. Kurihara, T.
J. Biosci. Bioeng.
117/ 5, 551-556
2014/05



17 Global identification of genes affecting iron-sulfur cluster biogenesis and iron homeostasis
Hidese, R. Mihara, H. Kurihara, T. Esaki, N.
J. Bacteriol.
196/ 6, 1238-1249
2014/01



18 Novel neogala-series glycosphingolipids with a terminal glucose residue from the fungus Mariannaea elegans
Tani, Y., Nakamura, K., Sawa, R., Nishio, M., Saito, S., Ito, M., Itonori, S., Mihara, H.
Biosci. Biotechnol. Biochem.
77, 754-759
2013/04



19 Effects of a supernatant from Aspergillus oryzae culture on the regulation of crassulacean acid metabolism (CAM) and pinitol biosynthesis in the common ice plant, Mesembryanthemum crystallinum L.
Saito, S., Yamano, K., Ueda, H., Tani, Y., Hayakawa, M., Tsuji, A., Mihara, H.
Trace Nutr. Res.
29, 51-57
2012



20 セレンディピティ
三原久明
バイオサイエンスとインダストリー
70, 144
2012



21 Pseudomonas putida PydR, a RutR-like transcriptional regulator, represses the dihydropyrimidine dehydrogenase gene in the pyrimidine reductive catabolic pathway
Hidese R, Mihara H, Kurihara T, Esaki N.
J. Biochem.
152, 341-346
2012/07



22 Structure and function of selenocysteine lyase and cysteine desulfurase
Mihara, H.
Amino Acids
41, S77-S78
2011



23 硫黄・セレン供給酵素群による含硫・含セレンバイオファクターの生成機構
三原久明
バイオサイエンスとインダストリー
69, 471-475
2011



24 鉄硫黄クラスター・セレンタンパク質生合成を司る酵素
三原久明
生化学
83, 1003-1015
2011



25 Mammalian selenocysteine lyase is involved in selenoprotein biosynthesis
Kurokawa, S., Takehashi, M., Tanaka, H., Mihara, H., Kurihara, T., Tanaka, S., Hill, K., Burk, R. & Esaki, N.
J Nutr Sci Vitaminol
57, 298-305
2011



26 Selenite Reduction by the Thioredoxin System: Kinetics and Identification of Protein-Bound Selenide
Tamura T, Sato K, Komori K, Imai T, Kuwahara M, Okugochi T, Mihara H, Esaki N, Inagaki K.
Biosci Biotechnol Biochem
75, 1184-1187
2011



27 Bacterial cysteine desulfurases: versatile key players in biosynthetic pathways of sulfur-containing biofactors
Hidese R, Mihara H, Esaki N.
Appl Microbiol Biotechnol
91, 47-61
2011



28 Identification of novel mammalian phospholipids containing threonine, aspartate, and glutamate as the base moiety
Omori T, Honda A, Mihara H, Kurihara T, Esaki N.
J Chromatogr B Analyt Technol Biomed Life Sci
879, 3296-3302
2011



29 Favourable effects of eicosapentaenoic acid on the late step of the cell division in a piezophilic bacterium, Shewanella violacea DSS12, at high-hydrostatic pressures
Kawamoto J, Sato T, Nakasone K, Kato C, Mihara H, Esaki N, Kurihara T.
Environ. Microbiol.
13, 2293-2298
2011



30 Escherichia coli dihydropyrimidine dehydrogenase is a novel NAD-dependent heterotetramer essential for the production of 5,6-dihydrouracil
Hidese R, Mihara H, Kurihara T, Esaki N.
J. Bacteriol.
193, 989-993
2011



31 Kenji Soda--researching enzymes with the spirit of an alpinist
Yoshimura T, Mihara H, Ohshima T, Tanizawa K.
J Biochem
148, 371-379
2010



32 The distribution of phosphatidyl-D-serine in the rat
Omori T, Mihara H, Kurihara T, Esaki N.
Biosci. Biotechnol. Biochem.
74, 1953-1955
2010



33 IscS Functions as a Primary Sulfur-donating Enzyme by Interacting Specifically with MoeB and MoaD in the Biosynthesis of Molybdopterin in Escherichia coli
Zhang, W., Urban, A., Mihara, H., Leimkühler, S., Kurihara, T. & Esaki, N.
J. Biol. Chem.
285, 2302-2308
2010



34 Reaction Mechanism and Molecular Basis for Selenium/Sulfur Discrimination of Selenocysteine Lyase
Omi, R., Kurokawa, S., Mihara, H., Hayashi, H., Goto, M., Miyahara, I., Kurihara, T., Hirotsu, K. & Esaki, N.
J. Biol. Chem.
285, 12133-12139
2010



35 Selenocysteine is Selectively Taken Up by Red Blood Cells
Imai, T., Mihara, H., Kurihara, T. & Esaki, N.
Biosci Biotechnol Biochem.
73, 2746-2748
2009



36 Crystal Structure of a Homolog of Mammalian Serine Racemase from Schizosaccharomyces pombe
Goto, M., Yamauchi, T., Kamiya, N., Miyahara, I., Yoshimura, T., Mihara, H., Kurihara, T., Hirotsu, K., Esaki, N.
J. Biol. Chem.
284, 25944-25952
2009



37 X-Ray Crystallographic and Mutational Studies of Fluoroacetate Dehalogenase from Burkholderia sp Strain FA1
Jitsumori, K., Omi, R., Kurihara, T., Kurata, A., Mihara, H., Miyahara, I., Hirotsu, K., Esaki, N.
J. Bacteriol.
191, 2630-2637
2009



38 Eicosapentaenoic acid plays a beneficial role in membrane organization and cell division of a cold-adapted bacterium, Shewanella livingstonensis Ac10
Kawamoto, J., Kurihara, T., Yamamoto, K., Nagayasu, M., Tani, Y., Mihara, H., Hosokawa, M., Baba, T., Sato, S.B., Esaki, N.
J. Bacteriol.
191, 632-640
2009



39 Occurrence of phosphatidyl-D-serine in the rat cerebrum
Omori, T., Mihara, H., Kurihara, T., Esaki, N.
Biochem. Biophys. Res. Commun.
382, 415-418
2009



40 Identification of proteins interacting with selenocysteine lyase
Tobe, R., Mihara, H., Kurihara, T., Esaki, N.
Biosci. Biotechnol. Biochem.
73, 1230-1232
2009



41 Serine racemase with catalytically active lysinoalanyl residue
Yamauchi, T., Goto, M., Wu, H.Y., Uo, T., Yoshimura, T., Mihara, H., Kurihara, T., Miyahara, I., Hirotsu, K., Esaki, N.
J. Biochem.
145, 421-424
2009



42 Functional analysis of two homologous mouse selenophosphate synthetases
Abe, K., Mihara, H., Nishijima, Y., Kurokawa, S., Esaki, N.
Biomed. Res. Trace Elem.
19, 76-79
2008



43 Characterization of human selenocysteine synthase involved in selenoprotein biosynthesis
Abe, K., Mihara, H., Tobe, R., Esaki, N.
Biomed. Res. Trace Elem.
19, 80-83
2008



44 Thioredoxin Reductase 1 Is Important for Selenoprotein Biosynthesis in HeLa Cells
Kurokawa, S., Mihara, H., Yokoyama, I., Mochizuki, M., Yodoi, J., Tamura, T., Kurihara, T., Esaki, N.
Biomed. Res. Trace Elem.
19, 84-87
2008



45 The iscS gene deficiency affects the expression of pyrimidine metabolism genes
Mihara, H., Hidese, R., Yamane, M., Kurihara, T., Esaki, N.
Biochem. Biophys. Res. Commun.
372, 407-411
2008



46 N-アルキルアミノ酸と環状イミノ酸の不斉合成に利用できる酵素
Muramatsu, H., Mihara, H., Kurihara, T., Esaki, N.
ファインケミカル
37, 12-21
2008



47 Selenite Assimilation into Formate Dehydrogenase H Depends on Thioredoxin Reductase in Escherichia coli
Takahata, M., Tamura, T., Abe, K., Mihara, H., Kurokawa, S., Yamamoto, Y., Nakano, R., Esaki, N., Inagaki, K.
J. Biochem.
143, 467-473
2008



48 Investigation of the Roles of Cysteine Desulfurases in the Molybdopterin Synthesis in Escherichia coli
Zhang, W., Mihara, H., Kurihara, T., Esaki, N.
Trace Nutri. Res.
25, 152-157
2008



49 モリブドプテリン生合成におけるシステインデスルフラーゼIscSの役割
Zhang, W., Mihara, H., Kurihara, T., Esaki, N.
ビタミン
82, 645-650
2008



50 Mining prokaryotic genomes for unknown amino acids: a stop-codon-based approach
Fujita, M., Mihara, H., Goto, S., Esaki, N., Kanehisa, M.
BMC Bioinformatics
8, 225
2007



51 セレンタンパク質
Mihara, H., Esaki, N.
金属
77, 262-268
2007



52 シュードモナスのリジン分解経路におけるミッシング酵素の同定と解析
Mihara, H., Esaki, N.
ビタミン
81, 595-600
2007



53 Prediction of missing enzyme genes in a bacterial metabolic network - Reconstruction of the lysine-degradation pathway of Pseudomonas aeruginosa
Yamanishi, Y., Mihara, H., Osaki, M., Muramatsu, H., Esaki, N., Sato, T., Hizukuri, Y., Goto, S., Kanehisa, M.
FEBS J.
274, 2262-2273
2007



54 Biochemical and genetic analysis of the γ-resorcylate (2,6-dihydroxybenzoate) catabolic pathway in Rhizobium sp strain MTP-10005: Identification and functional analysis of its gene cluster
Yoshida, M., Oikawa, T., Obata, H., Abe, K., Mihara, H., Esaki, N.
J. Bacteriol.
189, 1573-1581
2007



55 N-メチル-L-アミノ酸とL-ピペコリン酸の合成酵素 -An enzyme synthesizing N-methyl-L-amino acid and pipecolic acid-
Mihara H
バイオサイエンスとインダストリー

2006



56 代謝経路データベース上のミッシング酵素の同定 -Identification of missing enzymes in metabolic pathway databases-
Mihara H, Esaki N
バイオサイエンスとインダストリー

2006



57 セレン化合物とピリドキサール5´-リン酸酵素の生化学
Mihara H, Esaki N
Vitamins [ビタミン]

2006



58 Selenoprotein biosynthesis and selenium-specific enzymes
Mihara H, Kurokawa S, Omi R, Kurihara T, Hirotsu K, Esaki N
Biomed. Res. Trace Elem

2006



59 Enzymatic synthesis of L-pipecolic acid by Δ1-piperideine-2-carboxylate reductase from Pseudomonas putida
Muramatsu H, Mihara H, Yasuda M, Ueda M, Kurihara T, Esaki N
Biosci. Biotechnol. Biochem

2006



60 Enzymatic synthesis of cyclic amino acids by N-methyl-L-amino acid dehydrogenase from Pseudomonas putida
Yasuda, M., Ueda, M., Muramatsu, H., Mihara, H., Esaki, N.
Tetrahedron-Asymmet.
17, 1775-1779
2006



61 Protein interaction between selenophosphate synthetase and IscS
Abe K, Ebata I, Kazuoka T, Mihara H, Kurihara T, Esaki N
Biomed. Res. Trace Elem

2005



62 Crystal structures of Δ1-piperideine-2-carboxylate/Δ1-pyrroline-2-carboxylate reductase belonging to a new family of NAD(P)H-dependent oxidoreductases - Conformational change, substrate recognition, and stereochemistry of the reaction
Goto M, Muramatsu H, Mihara H, Kurihara T, Esaki N, Omi R, Miyahara I, Hirotsu K
J. Biol. Chem

2005



63 RNAi-mediated knock down of mammalian selenocysteine lyase
Kurokawa S, Mihara H, Takehashi M, Tanaka S, Kurihara T, Esaki N
Biomed. Res. Trace Elem

2005



64 N-Methyl-L-amino acid dehydrogenase from Pseudomonas putida - A novel member of an unusual NAD(P)-dependent oxidoreductase superfamily
Mihara H, Muramatsu H, Kakutani R, Yasuda M, Ueda M, Kurihara T, Esaki N
FEBS J

2005



65 A new family of NAD(P)H-dependent oxidoreductases distinct from conventional Rossmann-fold proteins
Muramatsu H, Mihara H, Goto M, Miyahara I, Hirotsu K, Kurihara T, Esaki N
J. Biosci. Bioeng

2005



66 The putative malate/lactate dehydrogenase from Pseudomonas putida is an NADPH-dependent Δ1-piperideine-2-carboxylate/Δ1-pyrroline-2-carboxylate reductase involved in the catabolism of D-lysine and D-proline
Muramatsu H, Mihara H, Kakutani R, Yasuda M, Ueda M, Kurihara T, Esaki N
J. Biol. Chem

2005



67 Expression analysis of mammalian selenocysteine lyase
Kurokawa S, Mihara H, Kurihara T, Esaki N
Biomed. Res. Trace Elem

2004



68 Enzymatic synthesis of N-methyl-L-phenylalanine by a novel enzyme, N-methyl-L-amino acid dehydrogenase, from Pseudomonas putida
Muramatsu H, Mihara H, Kakutani R, Yasuda M, Ueda M, Kurihara T, Esaki N
Tetrahedron: Asymmet

2004



69 鉄硫黄クラスター形成にかかわるピリドキサル酵素の機能、構造、触媒機構
Esaki N, Mihara H
ビタミン

2003



70 Assembly of iron-sulfur clusters mediated by cysteine desulfarases, IscS, CsdB and CSD, from Escherichia coli
Kurihara T, Mihara H, Kato S, Yoshimura T, Esaki N
Biochim. Biophys. Acta

2003



71 Effects of selenium deficiency on the expression of selenoprotein mRNAs in mouse brain
Kuwana E, Kurokawa S, Mihara H, Kurihara T, Yoshimura T, Esaki N
Biomed. Res. Trace Elem

2003



72 A novel regulatory function of selenocysteine lyase, a unique catalyst to modulate major urinary protein
Kwak MS, Mihara H, Esaki N
J. Mol. Cat. B-Enzym

2003



73 Enhanced selenium tolerance and accumulation in transgenic Arabidopsis expressing a mouse selenocysteine lyase
Pilon M, Owen JD, Garifullina GF, Kurihara T, Mihara H, Esaki N, Pilon-Smits EAH
Plant Physiol

2003



74 Characterization of a NifS-like chloroplast protein from Arabidopsis. Implications for its role in sulfur and selenium metabolism
Pilon-Smits EAH, Garifullina GF, Abdel-Ghany S, Kato SI, Mihara H, Hale KL, Burkhead JL, Esaki N, Kurihara T, Pilon M
Plant Physiology

2003



75 Cys-328 of IscS and Cys-63 of IscU are the sites of disulfide bridge formation in a covalently bound IscS/IscU complex: Implications for the mechanism of iron-sulfur cluster assembly
Kato S, Mihara H, Kurihara T, Takahashi Y, Tokumoto U, Yoshimura T, Esaki N
Proc. Natl. Acad. Sci. USA

2002



76 Protein Interaction between Selenocysteine Lyase and MUP-I
Kwak MS, Mihara H, Esaki N
Biomed. Res. Trace Elem

2002



77 Bacterial cysteine desulfurases: their function and mechanisms
Mihara H, Esaki N
Appl. Microbiol. Biotechnol

2002



78 Selenocysteine lyase from mouse liver
Mihara H, Esaki N
Method Enzymol

2002



79 セレンの生化学
Mihara H, Esaki N
ビタミン

2002



80 Structure of external aldimine of Escherichia coli CsdB, an IscS/NifS homolog: Implications for its specificity toward selenocysteine
Mihara H, Fujii T, Kato S, Kurihara T, Hata Y, Esaki N
J. Biochem

2002



81 The iscS gene is essential for the biosynthesis of 2-selenouridine in tRNA and the selenocysteine-containing formate dehydrogenase H
Mihara H, Kato S, Lacourciere GM, Stadtman TC, Kennedy RAJD, Kurihara T, Tokumoto U, Takahashi Y, Esaki N
Proc. Natl. Acad. Sci. USA

2002



82 in The 19th Symposium on Trace Nutrients Research [微量栄養素研究]
Mihara H, Kato S, Lacourciere GM, Stadtman TC, Kurihara T, Tokumoto U, Takahashi Y, Esaki N


2002



83 Characterization of a NifS-Like chloroplast protein from Arabidopsis. Implications for its role in sulfur and selenium metabolism
Pilon-Smits EAH, Garifullina GF, Abdel-Ghany S, Kato SI, Mihara H, Hale KL, Burkhead JL, Esaki N, Kurihara T, Pilon M
Plant Physiol

2002



84 Network of protein-protein interactions among iron-sulfur cluster assembly proteins in Escherichia coli
Tokumoto U, Nomura S, Minami Y, Mihara H, Kato S, Kurihara T, Esaki N, Kanazawa H, Matsubara H, Takahashi Y
J. Biochem

2002



85 Removal of soluble selenium by a selenate-reducing bacterium Bacillus sp. SF-1
Kashiwa M, Ike M, Mihara H, Esaki N, Fujita M
Biofactors

2001



86 in The 18th Symposium on Trace Nutrients Research [微量栄養素研究]
Kato S, Mihara H, Kurihara T, Yoshimura T, Esaki N


2001



87 Role of Cysteine Desulfurase in the Biosynthesis of Formate Dehydrogenase H Containing Mo, Molybdopterin, Selenocysteine, and Fe4S4 Cluster
Mihara H, Kato S, Kurihara T, Yoshimura T, Esaki N, Lacourciere GM, Stadtman TC
Biomed. Res. Trace Elem

2001



88 Structure of a NifS homologue: X-ray structure analysis of CsdB, an Escherichia coli counterpart of mammalian selenocysteine lyase
Fujii T, Maeda M, Mihara H, Kurihara T, Esaki N, Hata Y
Biochemistry

2000



89 Gene cloning, purification, and characterization of two cyanobacterial NifS homologs driving iron-sulfur cluster formation
Kato S, Mihara H, Kurihara T, Yoshimura T, Esaki N
Biosci. Biotechnol. Biochem

2000



90 in The 17th Symposium on Trace Nutrients Research [微量栄養素研究]
Kato S, Mihara H, Kurihara T, Yoshimura T, Esaki N


2000



91 Escherichia coli NifS-like proteins provide selenium in the pathway for the biosynthesis of selenophosphate
Lacourciere GM, Mihara H, Kurihara T, Esaki N, Stadtman TC
J. Biol. Chem

2000



92 cDNA cloning, purification, and characterization of mouse liver selenocysteine lyase - Candidate for selenium delivery protein in selenoprotein synthesis
Mihara H, Kurihara T, Watanabe T, Yoshimura T, Esaki N
J. Biol. Chem

2000



93 Kinetic and mutational studies of three NifS homologs from Escherichia coli: Mechanistic difference between L-cysteine desulfurase and L-selenocysteine lyase reaction
Mihara H, Kurihara T, Yoshimura T, Esaki N
J. Biochem

2000



94 in The 16th Symposium on Trace Nutrients Research [微量栄養素研究]
Esaki N, Mihara H, Kurihara T, Yoshimura T, Soda K


1999



95 A nifS-like gene, csdB, encodes an Escherichia coli counterpart of mammalian selenocysteine lyase - Gene cloning, purification, characterization and preliminary x-ray crystallographic studies
Mihara H, Maeda M, Fujii T, Kurihara T, Hata Y, Esaki N
J. Biol. Chem

1999



96 Cysteine sulfinate desulfinase, a NIFS-like protein of Escherichia coli with selenocysteine lyase and cysteine desulfurase activities. Gene cloning, purification, and characterization of a novel pyridoxal enzyme
Esaki N, Kurihara T, Yoshimura T, Soda K, Mihara H
ICR Annu. Report

1997



97 Cysteine sulfinate desulfinase, a NIFS-like protein of Escherichia coli with selenocysteine lyase and cysteine desulfurase activities - Gene cloning, purification, and characterization of a novel pyridoxal enzyme
Mihara H, Kurihara T, Yoshimura T, Soda K, Esaki N
J. Biol. Chem

1997



98 A new possibility to treatment of AIDS by selenium [セレンによるAIDS治療の可能性]
Mihara H
Vitamins

1995



99 Multiple Proline Substitutions Cumulatively Thermostabilize Bacillus cereus ATCC7064 Oligo-1,6-Glucosidase - Irrefragable Proof Supporting the Proline Rule
Watanabe K, Masuda T, Ohashi H, Mihara H, Suzuki Y
Eur. J. Biochem

1994



100 (博士取得論文)Enzymological Studies of Cysteine Desulfurase and Selenocysteine Lyase



1999/09