Researcher Database

（Last updated : 2025-04-07 14:10:58）　

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ISHIMIZU Takeshi

Department / Course College of Life Sciences Department of Biotechnology

Title / Position Professor

Other Affiliations
1.	Research Organization of Science and Technology Research Center for Biological Resources
2.	Graduate School of Life Sciences

Academic background
1.	～1993/03	Department of Chemistry │ Faculty of Science │ Osaka University │ Graduated Bachelor (Science)
2.	～1998/03	Doctoral Program (2nd Semester) │ Department of Organic Chemistry │ Graduate School, Division of Natural Science │ Osaka University │ Completed Ph.D (science)

Business career
1.	2024/04 ～	Associate Fellow │ │ Ritsumeikan Advanced Research Academy (RARA)

Research activities
1.		The Japanese Biochemical Society
2.		The Japanese Society of Applied Glycoscience
3.		The Japanese Society of Carbohydrate Research
4.		Japan Society for Bioscience, Biotechnology, and Agrochemistry
5.		The Japanese Society of Plant Physiologists
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Subject of research
1.	Biosynthesis and function of plant cell wall polysaccharides
2.	Biosynthesis and function of plant flavonoid glycosides
3.	Molecular mechanism of plant growth

Research summary
Elucidation of the biosynthesis and breakdown mechanism of a bio-energy source, plant sugar chains Plant sugar chain such as cellulose is attracting attention as a renewable energy source. However, plant sugar chain has a robust structure and is difficult to process, and is yet to become an alternative energy to replace fossil energy source. This being the case, biosynthesis and breakdown mechanism of the complex and robust structured plant sugar chain needs to be accurately elucidated in order to establish an efficient energy conversion technology. The biosynthesis and breakdown of plant sugar chain is a life phenomenon conducted by several enzymes, however, many of these enzymes have not been identified. The coordination of multiple enzymes is also an interesting subject for research. With these in the background, research is being conducted at Ishimizu Lab. to find the enzyme involved in the biosynthesis and breakdown of plant sugar chain and to elucidate the coordination of these multiple enzymes.

Present specialized field
Living Organism Molecular Science, Bio-related chemistry, Energy engineering, Molecular Biology, Structural Biochemistry, Functional Biochemistry, Plant Physiology/Molecule, Applied Biochemistry (Keyword：sugar chain, polysaccharide, protein, membrane protein, enzyme, biochemistry, plant, cell wall, bioenergy, bioethanol, biomass, genetically modified plant, environmentology)

Books
1.	2019/09	Glycoscience: Basic Science to Applications │ ,pp.112-113
2.	2014/10	Glycoscience: Biology and Medicine │ ,pp.1111-1117
3.	2009/06	Pectins and Pectinases │ ,pp.167-175
4.	2009/03	ピリジルアミノ化による糖鎖解析～糖鎖多様性の解析に向けて～
5.	2006/11	Endoglycosidases │ ,pp.74-83, 162-171, 239-245
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Papers
1.	2023/12	Biochemical characterization of parsley glycosyltransferases involved in the biosynthesis of a flavonoid glycoside, apiin. │ Int. J. Mol. Sci. │ 24,pp.17118
2.	2023/11	The apiosyltransferase celery UGT94AX1 catalyzes the biosynthesis of the flavone glycoside apiin. │ Plant Physiol. │ 193,pp.1758-1771
3.	2023/07	Lanthanum supplementation alleviates tomato root growth suppression under low light stress. │ Plants │ 12,pp.2663
4.	2023/04	FLOURY ENDOSPERM 6 mutations enhance the sugary phenotype caused by the loss of ISOAMYLASE1 in barley. │ 136,pp.94
5.	2022/10	Structural features of free N-glycans in α1,3/4-fucosidase-deficient Arabidopsis thaliana: deletion of α1,3/4-fucosidase activity induced accumulation of plant complex type GN1 free N-glycans. │ Biosci. Biotechnol. Biochem. │ 86,pp.1413-1416
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Academic conference presentation
1.	2023/03/15	Recombinant protein expression of an arabinofuranosyl transferase involved in arabinoxylan biosynthesis in Setaria viridis
2.	2022/08/31	Identification and biochemical characterization of parsley apiosyltransferase involved in apiin biosynthesis
3.	2022/06/15	Biochemical characterization of glycosyltransferases involved in pectin RG-I backbone biosynthesis
4.	2019/11/10	Pectin RG-I rhamnosyltransferases in Marchantia polymorpha
5.	2019/07/09	Biochemical　characterization of pectin rhamnogalacturonan I galactosyltransferase
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External Researcher ID
ORCID ID
https://orcid.org/0000-0003-4910-6810