Researcher Database

（Last updated : 2026-07-06 16:37:08）　

KOIKE Chieko

Department / Course College of Pharmaceutical Sciences Department of Pharmaceutical Sciences

Title / Position Professor

Other Affiliations
1.	Graduate School of Pharmacy
2.	Research Organization of Science and Technology Center for Systems Vision Science

Academic background
1.		Ph.D. (Pharmaceutical Sciences)

Business career
1.	2015/04/01 ～	Director │ │ Center for Systems Vision Science

Committee and society
1.	2026/01/01 ～	The Japanese Neuroscience Society Councilor
2.	2023/11/01 ～ 2024/06/22	57th annual meeting of the Japanese Society of Developmental Biologists
3.	2019/04 ～ 2019/08	15th Asia-Pacific Conference on Vision (APCV) 2019 Committee members
4.	2018/04 ～ 2018/09	Vision Science forum 2018 Chair of organizing committee

Research activities
1.		Vision Science Forum
2.		The Association for Research in Vision and Ophthalmology
3.		The Society for Neuroscience
4.		The Japan Neuroscience Society
5.		The Pharmaceutical Society of Japan

Research summary
Generation of vertebrate retina and systems biology of functions Many of our recognition and behaviors in our daily life depend on the visual information. Retina that belongs to central nerve system is the only nerve tissue that converts light information to neural information. It is known that the visual information is processed in the visual cortex of our cerebrum but an important process is performed in our retina at first.

Present specialized field
Neurophysiology / General neuroscience, Molecular Biology, Cell Biology, Developmental Biology, Biological pharmacy, Pharmacology in pharmacy (Keyword：Central nervous systems retina vision polarity adhesion bipolar photoreceptor)

Papers
1.	2026	Pathological Retinal Oscillations Across Retinal Diseases: Shared Circuit Mechanisms and Implications for Photopsia │ Biol. Pharm. Bull. │ ,pp.in press
2.	2025/12/22	Afadin-deficient retinas exhibit severe neuronal lamination defects but preserve visual functions │ eLife │ Dec22 (14),pp.RP105627
3.	2025/11	A mechanism for pathological oscillations in mouse retinal ganglion cells in a model of night blindness │ Journal of General Physiology │ 157 (6),pp.e202413749
4.	2025/08	Hidden Markov models reveal behavioral state dynamics in depth-related locomotion in mice │ PLOS One │ 20 (8),pp.e0329367
5.	2025/07	Hidden Markov Model-Based Behavioral Classification Reveals Visual Function Recovery After Retinal Organoid Transplantation in Mice │ J Neurosci Res │ 103 (7),pp.e70068
Display All（68）

Academic conference presentation
1.	2026/06/10	Preserved Visual Behaviors Despite Severe Retinal Lamination Defects in Afadin Conditional Knockout Mice
2.	2026/06/09	Loss of TRPM1 leads to pathological oscillations in the retina
3.	2026/03/11	マウス網膜における病的オシレーション発生メカニズムの解明
4.	2024/10/31	A common mechanism for pathological retinal ganglion cell oscillations in the mouse retina
5.	2024/10/08	A common mechanism for pathological ganglion cell oscillations in the Trpm1 KO and rd1 mouse retinas
Display All（55）

Works
1.	2026/05/31	Retinal function in health and diseases: Preservation and breakdown of signaling
2.	2025/11/21	Retinal Robustness
3.	2025/08/26	How Robust is the Retina? Visual Responses in a Severely Disorganized Circuit (仁川)
4.	2021/11/16	Loss of TRPM1, a cause of congenital stationary night blindness, is associated with abnormal non-visual behaviors in the mouse (Chicago)

Achievements of joint.Funded research
1.	2022/01/01 ～ 2023/12/31	Nanostructure of the mammalian cone photoreceptor synapse in adult, developing, and in vitro 3D retinas │ International Joint Research

Home Page
Center for Systems Vision Science