Researcher Database

（Last updated : 2025-01-20 01:41:52）　

KOIKE Chieko

Department / Course College of Pharmaceutical Sciences Department of Pharmaceutical Sciences

Title / Position Professor

Other Affiliations
1.	Graduate School of Pharmacy
2.	Research Organization of Science and Technology Center for Systems Vision Science

Academic background
1.		Ph.D. (Pharmaceutical Sciences)

Business career
1.	2015/04/01 ～	Director │ │ Center for Systems Vision Science

Committee and society
1.	2023/11/01 ～ 2024/06/22	57th annual meeting of the Japanese Society of Developmental Biologists
2.	2019/04 ～ 2019/08	15th Asia-Pacific Conference on Vision (APCV) 2019 Committee members
3.	2018/04 ～ 2018/09	Vision Science forum 2018 Chair of organizing committee

Research activities
1.		Vision Science Forum
2.		The Association for Research in Vision and Ophthalmology
3.		The Society for Neuroscience
4.		The Japan Neuroscience Society
5.		The Pharmaceutical Society of Japan

Research summary
Generation of vertebrate retina and systems biology of functions Many of our recognition and behaviors in our daily life depend on the visual information. Retina that belongs to central nerve system is the only nerve tissue that converts light information to neural information. It is known that the visual information is processed in the visual cortex of our cerebrum but an important process is performed in our retina at first.

Present specialized field
Neurophysiology / General neuroscience, Molecular Biology, Cell Biology, Developmental Biology, Biological pharmacy, Pharmacology in pharmacy (Keyword：Central nervous systems retina vision polarity adhesion bipolar photoreceptor)

Papers
1.	2025	Afadin-deficient retinas exhibit severe neuronal lamination defects but preserve visual functions. │ eLife │ (Co-authored)
2.	2025	Transplantation of genome edited retinal organoids restores light-adapted retinal function in the retina of advanced retinal degeneration │ Stem Cell Report │ (Co-authored)
3.	2023/12/20	Adaptation of organisms to high-hydrostatic pressure environments │ The Cell │ ,pp.1153-1157 (Co-authored)
4.	2023/03/17	Effects of Astaxanthin, Lutein, and Zeaxanthin on Eye-Hand Coordination and Smooth-Pursuit Eye Movement after Visual Display Terminal Operation in Healthy Subjects: A Randomized, Double-Blind Placebo-Controlled Intergroup Trial │ Nutrients │ 15 (6),pp.1459 (Co-authored)
5.	2022/11/14	Mathematical analysis of phototransduction reaction parameters in rods and cones │ Scientific Reports │ 12 (1),pp.19529 (Co-authored)
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Academic conference presentation
1.	2024/10/31	A common mechanism for pathological retinal ganglion cell oscillations in the mouse retina (日仏合同セミナー)
2.	2024/10/08	A common mechanism for pathological ganglion cell oscillations in the Trpm1 KO and rd1 mouse retinas (Neuroscience2024)
3.	2024/07/24	Electrophysiological analysis of retinal circuit formation in the wild-type and channelrhodopsin-2 expressed mice during development (Neuro2024)
4.	2024/07/24	Mechanistic Analysis of the Development of Psychiatric Disease-like Behaviors in Trpm1 Knockout Mice (Neuro2024)
5.	2024/06	Differential response to high-pressure on a variety of culture cells derived from homeothermic animals
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Works
1.	2021/11/16	Loss of TRPM1, a cause of congenital stationary night blindness, is associated with abnormal non-visual behaviors in the mouse (Chicago)

Achievements of joint.Funded research
1.	2022/01/01 ～ 2023/12/31	Nanostructure of the mammalian cone photoreceptor synapse in adult, developing, and in vitro 3D retinas │ International Joint Research