Researcher Database

（Last updated : 2024-04-21 11:27:15）

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TOYOTAKE YOSUKE

Department / Course College of Life Sciences Department of Biotechnology

Title / Position Assistant Professor

Academic background
1.	2019/03 Degree Acquisition	│ Kyoto University Doctor of Agricultural Science
2.	2016/04～2019/03	Doctoral Program (2nd Semester) │ Division of Applied Life Sciences │ Graduate School of Agriculture │ Kyoto University │ Completed
3.	2014/04～2016/03	Master Course │ Division of Applied Life sciences │ Graduate School of Agriculture │ Kyoto University │ Completed
4.	2010/04～2014/03	Department of Biological Sciences │ School of Sciences │ Osaka University │ Graduated

Business career
1.	2024/04 ～	Assistant Professor │ College of Life Sciences, Department of Biotechnology │ Ritsumeikan University
2.	2023/11 ～ 2024/03	Guest Scientist (Concurrent) │ B CUBE Center for Molecular Bioengineering │ Dresden University of Technology
3.	2019/04 ～ 2024/03	Assistant Professor │ College of Life Sciences, Department of Biotechnology │ Ritsumeikan University

Research activities
1.		The Japanese Biochemical Society
2.		The Japanese Conference on the Biochemistry of Lipids
3.		The Japan Society for Bioscience, Biotechnology, and Agrochemistry
4.		The Society of Biotechnology, Japan
5.		Extremophiles

Subject of research
1.	Investigation of the molecular bases underlying the unique metabolic activities of microorganisms and their biotechnological application
2.	Physiological function analysis of enzymes related to lipid metabolism

Present specialized field
Applied microbiology, Functional biochemistry, Bio-related chemistry, Food science (Keyword：Lipid biochemistry, Microbial biology, Environmental response, Oxidative fermentation, Biological membrane, Phospholipid, Hopanoid, Fatty acid)

Papers
1.	2024/05	Preparation and characterization of a novel amphiphilic nanocarrier based on enzymatic polymerization-derived α-1,3-glucan for efficient quercetin encapsulation │ Colloid and Polymer Science │ in press (Co-authored)
2.	2023/08	Synthesis and characterization of a novel self-assembled amphiphilic α-1,3-glucan nanomicelles for drug delivery │ Colloid and Polymer Science │ 301,pp.1337–1350 (Co-authored)
3.	2023/01	Characterization of three γ-glutamyltranspeptidases from Pseudomonas aeruginosa PAO1 │ The Journal of General and Applied Microbiology │ 69 (3),pp.150-158 (Co-authored)
4.	2021/10	Development of the original whey-based vinegar using rapeseed meal or wheat bran as a raw material for koji │ Journal of Food Processing and Preservation │ 45 (12),pp.e16097 (Co-authored)
5.	2021/10	Initial step of selenite reduction via thioredoxin for bacterial selenoprotein biosynthesis │ International Journal of Molecular Sciences │ 22 (20),pp.10965 (Co-authored)
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Academic conference presentation
1.	2023/08	Structural diversity and its physiological significance of plasma membrane lipids for the unique fermentation physiology of acetic acid bacteria (Japanese Society for Extremophiles 2023)
2.	2023/08	Construction and phenotypic analysis of mutant strains deficient in the homologs of squalene cyclase of acetic acid bacteria (Japanese Society for Extremophiles 2023)
3.	2023/08	Physiological function analysis of lysophospholipid acyltransferase homologs from acetic acid bacteria (Japanese Society for Extremophiles 2023)
4.	2023/03	Formation of extracellular selenium nanoparticles by Escherichia coli requires integrity of membrane structure and normal membrane vesicle formation (The 2023 Annual Meeting of the Japan Society for Bioscience, Biotechnology, and Agrochemistry)
5.	2023/03	Synthesis and charaterization of Quercetin loaded α-1,3-glucan-graft-poly(ε-caprolactone) nanomicelles (The 2023 Annual Meeting of the Japan Society for Bioscience, Biotechnology, and Agrochemistry)
Display All（26）

Winning science prize
1.	2022/11	Japanese Society for Extremophiles Poster Award (Analysis of phosphatidylcholine-regulated membrane functions of acetic acid bacteria)

Grants-in-Aid for Scientific Research -KAKENHI-
1.	2023/09 ～	Exploration and application of extracellular membrane vesicle-producing bacteria as a basic technology for aquaculture augmentation │ Fund for the Promotion Joint International Research（Fostering Joint International Research）(B)
2.	2023/04 ～	Elucidation of the physiological functions of bacterial membrane phospholipids and their functional expression mechanisms using acetic acid bacteria as a model │ Early-Career Scientists
3.	2021/04 ～ 2024/03	Elucidation of the acetic acid response mechanism depending on the phospholipid acyl chain structure of acetic acid bacteria │ Early-Career Scientists

Achievements of joint.Funded research
1.	2024/04 ～ 2025/03	Reverse genetic and biochemical analysis of cell membrane functions in acetic acid bacteria
2.	2024/04 ～ 2025/03	Analysis of membrane lipid-dependent fermentation stress response in acetic acid bacteria

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