Researcher Database

SUZUKI Kenji

Department / Course College of Pharmaceutical Sciences Department of Pharmaceutical Sciences

Title / Position Professor

Papers
1.	2021	Protein kinases A and C regulate amyloid-β degradation by modulating protein levels of neprilysin and insulin-degrading enzyme in astrocytes. │ Neurosci. Res. │ 166,pp.62-72 (Co-authored)
2.	2020	Multiple nuclear localization sequences in SRSF protein. │ Genes Cells │ 25,pp.327-333 (Co-authored)
3.	2020	The cysteine residue at 424th of pyruvate kinaseM2 is crucial for tetramerization and responsiveness to oxidative stress. │ Biochem. Biophys. Res. Commun. │ 526,pp.973-977 (Co-authored)
4.	2019	Myelodysplastic Syndrome-Associated SRSF2Mutations Cause Splicing Changes by Altering Binding Motif Sequences. │ Front. Genet │ 10 (Co-authored)
5.	2018/08	Insulin-signaling Pathway Regulates the Degradation of Amyloid β-protein via Astrocytes. │ Neuroscience │ 385,pp.227-236 (Co-authored)
6.	2017/01	The σ1 receptor regulates accumulation of GM1 ganglioside-enriched autophagosomes in astrocytes. │ Neuroscience │ 340,pp.176-187 (Co-authored)
7.	2016/07	Biological roles and therapeutic potential of G protein-coupled receptors for free fatty acids and metabolic intermediates. │ J. Phys. Fitness Sports Med. │ 5 (3),pp.213-227 (Co-authored)
8.	2016/02	Simvastatin and atorvastatin facilitates amyloid β-protein degradation in extracellular spaces by increasing neprilysin secretion from astrocytes through activation of MAPK/Erk1/2 pathways. │ Glia │ (Co-authored)
9.	2015/12	Effect of Circadian Rhythm on Clinical and Pathophysiological Conditions and Inflammation. │ Crit. Rev. Immunol. │ 35 (4),pp.261-275 (Co-authored)
10.	2015/03	Mechanical stress regulates gene expression via Rho/Rho-kinase signaling pathway. │ J. Phys. Fitness Sports Med. │ 4 (1),pp.53-61 (Co-authored)
11.	2015/02	Midazolam inhibits the formation of amyloid fibrils and GM1 ganglioside-rich microdomains in presynaptic membranes through the gamma-aminobutyric acid A receptor. │ Biochem. Biphys. Res. Commun. │ 447 (4),pp.547-553 (Co-authored)
12.	2014/07	Leptin inhibits amyloid β-protein fibrillogenesis by decreasing GM1 gangliosides on the neuronal cell surface through PI3K/Akt/mTOR pathway. │ J. Neurochem. │ 131 (3),pp.323-332 (Co-authored)
13.	2014/02	Leptin inhibits amyloid β-protein degradation through decrease of neprilysin expression in primary cultured astrocytes. │ Biochem. Biphys. Res. Commun. │ 445 (1),pp.214-217 (Co-authored)
14.	2013/06	Ketamine reduces amyloid β-protein degradation by suppressing neprilysin expression in primary cultured astrocytes. │ Neurosci. Lett. │ 545,pp.54-58 (Co-authored)
15.	2013/06	Propofol and thiopental suppress amyloid fibril formation and GM1 ganglioside expression through the gamma-aminobutyric acid A receptor. │ Anesthesiology │ 118 (6),pp.1408-1416 (Co-authored)
16.	2012/08	Comparative proteomic analysis reveals differentially expressed proteins in Caenorhabditis elegant pgl-1 mutants grown at 20 ℃ and 25 ℃ │ J. Proteomics │ 75 (15),pp.4792-4801 (Co-authored)
17.	2012/06	Dynamic Regulation of Myosin Light Chain Phosphorylation by Rho-kinase │ PLoS ONE │ 7 (6),pp.1-9 (Co-authored)
18.	2012/05	Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes. │ J. Neurochem. │ 121 (4),pp.619-628 (Co-authored)
19.	2010/05	Insulin inhibits Abeta fibrillogenesis through a decrease in the GM1 ganglioside-rich microdomain of neuronal membranes. │ J. Neurochem. │ 113 (3),pp.628-636 (Co-authored)
20.	2008	Species differences between human and rat in the substrate specificity of cathepsin k │ J. Biochem. │ 144,pp.499-506 (Co-authored)
21.	2007	Gliclazide inhibits proliferation but stimulates differentiation of white and brown adipocytes │ J. Biochem. │ 142,pp.639-645 (Co-authored)
22.	2007	SHP-2 positively regulates adipogenic differentiation in 3T3-L1 cells │ Int. J. Mol. Med. │ 19,pp.895-900 (Co-authored)
23.	2007	Transcription regulation of gene expression in rat brown adipose tissue in response to unloading or 2G loading during growth period │ Acta Astronautica │ 60,pp.889-898 (Co-authored)
24.	2005	Is Angiotensin-I Converting Enzyme I/D polymorphism Associated with Endurance Performance and/or High Altitude Adaptation │ Adv. Exerc. Sports Physiol. │ 11,pp.41-54 (Co-authored)
25.	2003	Effect of Eccentric Exercise on Neutrophil Function in Human Plasma │ Adv. Exerc. Sports Physiol │ ,pp.9(2): 69-75 (Co-authored)
26.	2003	Genetic variation in hypoxia-inducible factor 1-alpha and its possible association with high altitude adaptation in Sherpas │ Med. Hypotheses │ ,pp.61(3): 385-389 (Co-authored)
27.	2003	Gliclazide protects pancreatic beta-cells from damage by hydrogen peroxide │ Biochem. Biophys. Res. Commun. │ ,pp.303: 112-119 (Co-authored)
28.	2003	Intermittent Hypobaric Hypoxia Increases the Ability of Neutrophils to Generate Superoxide Anion in Humans │ Clin. Exp. Pharmacol. Physiol │ ,pp.30(9): 659-664 (Co-authored)
29.	2003	Physical Exercise and Extracellulrar Superoxide ismutase: Antiatherogenic Effects │ Adv. Exerc. Sports Physiol. │ ,pp.9(2): 45-53 (Co-authored)
30.	2002	Brain-Derived Neurotrophic Factor Promotes Interaction of the Nck2 Adaptor Protein with the TrkB Tyrosine Kinase Receptor │ Biochem.Biophys.Res.Commun │ ,pp.294:1087-1092 (Co-authored)
31.	2002	Stress- and Aging-Associated Modulation of Macrophage Functions │ Environmental Health Preventive Medicine │ ,pp.6(4): 218-228 (Co-authored)
32.	2001	Activation and Apoptosis of Murine Peritoneal Macrophages by Acute Cold Stress │ Biochem. Biophys. Res. Commun │ ,pp.283: 700-706 (Co-authored)
33.	2001	Analysis of Tyrosine Phosphorylation-Dependent Protein-Protein Interactions in TrkB-Mediated Intracellular Signaling Using Modified Yeast Two-Hybrid System │ J.Biochem.(Tokyo) │ ,pp.130(1):157-165 (Co-authored)
34.	2001	Negative regulation of LPS-stimulated expression of inducible nitric oxide synthase by AP-1 in macrophage cell line J774A.1 │ Biochem. Biophys. Res. Commun │ ,pp.289(5): 1031-1038 (Co-authored)
35.	2001	Physical Exercise and Uncoupling Protein Family │ Adv. Exerc. Sports Physio │ ,pp.7(1): 1-15 (Co-authored)
36.	2000	Exercise and antioxidant enzymes in skeletal muscle │ Recent Res. Dev. Endocrinol │ ,pp.1: 155-164 (Co-authored)
37.	2000	EXTRACELLULAR ATP INHIBITS THE STARVATION-INDUCED APOPTOSIS VIA P2X2 RECEPTORS IN DIFFERENTIATED RAT PHEOCHROMOCYTOMA PC12 CELLS │ Life Sci │ ,pp.66:1849-1859 (Co-authored)
38.	2000	Serum extracellular superoxide dismutase in pediatric patients with various diseases as judged by an ELISA │ Res. Commun. Mol. Pathol. Pharmacol │ ,pp.107(3,4): 291-296 (Co-authored)
39.	1999	Effects of acute cold stress on mRNA expression and immunoreactivity of three superoxide dismutase isoenzymes in genetically obese mice │ Res. Commun. Mol. Pathol. Pharmacol │ ,pp.106(1, 2): 47-61 (Co-authored)
40.	1999	The entry of new members in the signal transduction of Trk │ Recent Res. Dev. Biochem │ ,pp.1:169-177 (Co-authored)
41.	1990	Elucidation of amidating reaction mechanism by frog amidating enzyme, peptidylglycine α-hydroxylating monooxygenase, expressed in insect cell culture. │ EMBO J . │ 9,pp.4259-4265