Researcher Database

SUGANO KIYOHIKO

Department / Course College of Pharmaceutical Sciences Department of Pharmacy

Title / Position Professor

Papers
1.	2023/02	Dissolution Profiles of Carbamazepine Cocrystals with Cis-Trans Isomeric Coformers. │ Pharmaceutical research │ 40 (2),pp.579-591 (Co-authored)
2.	2023/02	Prediction of Oral Drug Absorption in Rats from In Vitro Data. │ Pharmaceutical research │ 40 (2),pp.359-373 (Co-authored)
3.	2023/01	Development of bicarbonate buffer flow-through cell dissolution test and its application in prediction of in vivo performance of colon targeting tablets. │ European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences │ 180,pp.106326 (Co-authored)
4.	2022/11	Thermodynamic Correlation between Liquid-Liquid Phase Separation and Crystalline Solubility of Drug-Like Molecules. │ Pharmaceutics │ 14 (12) (Co-authored)
5.	2022/05	A Critical Overview of the Biological Effects of Excipients (Part II): Scientific Considerations and Tools for Oral Product Development. │ The AAPS journal │ 24 (3),pp.61 (Co-authored)
6.	2022/01	Is equilibrium slurry pH a good surrogate for solid surface pH during drug dissolution? │ European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences │ 168,pp.106037 (Co-authored)
7.	2022/01	Salt Solubility and Disproportionation - Uses and Limitations of Equations for pHmax and the In-silico Prediction of pHmax. │ Journal of pharmaceutical sciences │ 111 (1),pp.225-246 (Co-authored)
8.	2022	Effect of divalent and trivalent metal ions on artificial membrane permeation of fluoroquinolones. │ ADMET & DMPK │ 10 (4),pp.289-297 (Co-authored)
9.	2021/12	Dissolution Kinetics of Nifedipine-Ionizable Polymer Amorphous Solid Dispersion: Comparison Between Bicarbonate and Phosphate Buffers. │ Pharmaceutical research │ 38 (12),pp.2119-2127 (Co-authored)
10.	2021/04	Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network. │ Advanced drug delivery reviews │ 171,pp.289-331 (Co-authored)
11.	2021	Lost in modelling and simulation? │ ADMET & DMPK │ 9 (2),pp.75-109 (Sole-authored)
12.	2020/10	Effects of Coformer and Polymer on Particle Surface Solution-Mediated Phase Transformation of Cocrystals in Aqueous Media. │ Molecular pharmaceutics │ 17 (10),pp.3825-3836 (Co-authored)
13.	2020/09	Bottom-Up Physiologically Based Oral Absorption Modeling of Free Weak Base Drugs. │ Pharmaceutics │ 12 (9) (Co-authored)
14.	2020/09	Effect of Cerebrospinal Fluid Circulation on Nose-to-Brain Direct Delivery and Distribution of Caffeine in Rats. │ Molecular pharmaceutics │ (Co-authored)
15.	2020/09	Prediction of negative food effect induced by bile micelle binding on oral absorption of hydrophilic cationic drugs. │ European journal of pharmaceutical sciences │ 155,pp.105543 (Co-authored)
16.	2020/08	The Critical Role of Passive Permeability in Designing Successful Drugs. │ ChemMedChem │ (Co-authored)
17.	2020/03	Prediction Characteristics of Oral Absorption Simulation Software Evaluated Using Structurally Diverse Low-Solubility Drugs. │ Journal of pharmaceutical sciences │ 109 (3),pp.1403-1416 (Co-authored)
18.	2020	Permeation characteristics of tetracyclines in parallel artificial membrane permeation assay II: Effect of divalent metal ions and mucin. │ ADMET & DMPK │ 8 (2),pp.129-138 (Co-authored)
19.	2019/08	Prediction Accuracy of Mechanism-Based Oral Absorption Model for Dogs. │ Journal of pharmaceutical sciences │ 108 (8),pp.2728-2736 (Co-authored)
20.	2019/04	Mechanism of Supersaturation Suppression in Dissolution Process of Acidic Drug Salt. │ Molecular pharmaceutics │ 16 (4),pp.1669-1677 (Co-authored)
21.	2018/11	Precipitation behavior of pioglitazone on the particle surface of hydrochloride salt in biorelevant media. │ Journal of pharmaceutical and biomedical analysis │ 161,pp.45-50 (Co-authored)
22.	2018/09	Evaluation of Using Dogs to Predict Fraction of Oral Dose Absorbed in Humans for Poorly Water-Soluble Drugs. │ Journal of pharmaceutical sciences │ 107 (9),pp.2489-2496 (Co-authored)
23.	2018	Precipitation behavior of pioglitazone on the particle surface of hydrochloride salt in biorelevant media │ J. Pharm. Biomed. Anal │ 161 (30),pp.45-50
24.	2016	Effect of seed particles on precipitation of weak base drugs in physiological intestinal conditions │ Mol. Pharmaceutics │ 13 (8),pp.2711-2717
25.	2015/12	Coning phenomena under laminar flow. │ European journal of pharmaceutical sciences │ 80,pp.53-5 (Co-authored)
26.	2015/09	Triboelectrification of active pharmaceutical ingredients: week acids and their salts. │ International journal of pharmaceutics │ 493 (1-2),pp.434-8 (Co-authored)
27.	2015	Coning phenomena under laminar flow │ Eur. J. Pharm. Sci. │ 80 (1),pp.53-55 (Co-authored)
28.	2015	Identification and physicochemical characterization of caffeine citric acid co-crystal polymorphs │ Eur. J. Pharm. Sci. │ 79 (15),pp.61-66 (Co-authored)
29.	2015	Stability order of caffeine co-crystals determined by co-crystal former exchange reaction and its application for the validation of in silico models. │ Chemical & pharmaceutical bulletin │ 63 (1),pp.18-24 (Co-authored)
30.	2014/12	Minimum rotation speed to prevent coning phenomena in compendium paddle dissolution apparatus. │ European journal of pharmaceutical sciences │ 65,pp.74-8 (Co-authored)
31.	2014/11	Application of the BCS biowaiver approach to assessing bioequivalence of orally disintegrating tablets with immediate release formulations. │ European journal of pharmaceutical sciences │ 64,pp.37-43 (Co-authored)
32.	2014/07	Permeability comparison between hepatocyte and low efflux MDCKII cell monolayer. │ The AAPS journal │ 16 (4),pp.802-9 (Co-authored)
33.	2014	Minimum rotation speed to prevent coning phenomena in compendium paddle dissolution apparatus │ Eur. J. Pharm.Sci. │ 65 (18),pp.74-78 (Co-authored)
34.	2014	Physicochemical and crystal structure analysis of pranlukast pseudopolymorphs I: anhydrates and hydrate │ J. Pharm. Biomed. Anal. │ 107 (25),pp.42690 (Co-authored)
35.	2011/02	Fraction of a dose absorbed estimation for structurally diverse low solubility compounds. │ International journal of pharmaceutics │ 405 (1-2),pp.79-89 (Sole-authored)
36.	2010/10	Aqueous boundary layers related to oral absorption of a drug: from dissolution of a drug to carrier mediated transport and intestinal wall metabolism. │ Molecular pharmaceutics │ 7 (5),pp.1362-73 (Sole-authored)
37.	2010/10	Computational oral absorption simulation of free base drugs. │ International journal of pharmaceutics │ 398 (1-2),pp.73-82 (Sole-authored)
38.	2010/08	Coexistence of passive and carrier-mediated processes in drug transport. │ Nature reviews. Drug discovery │ 9 (8),pp.597-614 (Co-authored)
39.	2009/05	Theoretical investigation of passive intestinal membrane permeability using Monte Carlo method to generate drug-like molecule population. │ International journal of pharmaceutics │ 373 (1-2),pp.55-61 (Sole-authored)
40.	2009/03	Introduction to computational oral absorption simulation. │ Expert opinion on drug metabolism & toxicology │ 5 (3),pp.259-93 (Sole-authored)
41.	2009/02	Estimation of effective intestinal membrane permeability considering bile micelle solubilisation. │ International journal of pharmaceutics │ 368 (1-2),pp.116-22 (Sole-authored)
42.	2009	A simulation of oral absorption using classical nucleation theory │ Int. J. Pharm. │ ,pp.142-145 (Sole-authored)
43.	2008/11	Theoretical comparison of hydrodynamic diffusion layer models used for dissolution simulation in drug discovery and development. │ International journal of pharmaceutics │ 363 (1-2),pp.73-7 (Sole-authored)
44.	2007/08	Solubility and dissolution profile assessment in drug discovery. │ Drug metabolism and pharmacokinetics │ 22 (4),pp.225-54 (Co-authored)
45.	2006/10	High throughput solubility measurement with automated polarized light microscopy analysis. │ Journal of pharmaceutical sciences │ 95 (10),pp.2115-22 (Co-authored)
46.	2006/10	Physicochemical and cell-based approach for early screening of phospholipidosis-inducing potential. │ The Journal of toxicological sciences │ 31 (4),pp.315-24 (Co-authored)
47.	2006	Predicting Oral Absorption of Poorly Water-Soluble Drugs Using an Integrated System of a Miniscale Dissolution Test and Computer Simulation │ Pharm.Res │ 23,pp.1144-1156 (Co-authored)
48.	2004/05	Correction of permeability with pore radius of tight junctions in Caco-2 monolayers improves the prediction of the dose fraction of hydrophilic drugs absorbed by humans. │ Pharmaceutical research │ 21 (5),pp.749-55 (Co-authored)
49.	2004/05	Permeation characteristics of a hydrophilic basic compound across a bio-mimetic artificial membrane. │ International journal of pharmaceutics │ 275 (1-2),pp.271-8 (Co-authored)
50.	2004/02	Biopharmaceutics classification by high throughput solubility assay and PAMPA. │ Drug development and industrial pharmacy │ 30 (2),pp.181-5 (Co-authored)
51.	1995/10/15	Alkyl Radical Substitution on Disulfide in the Presence of Cobalt(II) Complexes │ Bulletin of the Chemical Society of Japan │ 68 (10),pp.2969-2973 (Co-authored)
52.	1995	Alkyl Radical Substitution on Disulfide in the Presence of Cobalt(II) Complexes. │ Bulletin of the Chemical Society of Japan │ 68 (10),pp.2969-2973 (Co-authored)