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SHIRAKABE KYOKO
Department / Course
College of Life Sciences Department of Biomedical Sciences
Title / Position
Professor
Papers
1.
2020
Negatively charged amino acids in the stalk region of membrane proteins reduce ectodomain shedding. │ J Biol Chem. │ in press
2.
2019/06
LRRK1 phosphorylation of Rab7 at S72 links trafficking of EGFR-containing endosomes to its
effector RILP │ J Cell Sci │ 132 (11)
3.
2019/01
プロテオーム解析から明らかになったシェディングの役割と制御機構、化学と生物 │ ,pp.15-20
4.
2017
Mechanistic insights into ectodomain shedding:
susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation │ Sci Rep. │ 7,pp.46174
5.
2017
Secretome analysis to elucidate metalloprotease-dependent ectodomain shedding of
glycoproteins during neuronal differentiation. │ Genes Cells │ 22 (2),pp.237-244
6.
2014
A proteomic
approach for the elucidation of stimulus- and substrate-specificity of ectodomain shedding. │ J. Proteomics. │ 98,pp.233-243
7.
2011
VIP36 protein is a target of ectodomain shedding and regulates phagocytosis in macrophage Raw 264.7 cells. │ J Biol Chem. │ 286 ((50)),pp.43154-43163
8.
2006
IRBIT, an inositol 1,4,5-triphosphate receptor-binding protein, specifically binds to and
activates pancreas-type Na+/HCO3- cotransporter 1 (pNBC1). │ Proc Natl Acad Sci USA. │ 103 (25),pp.9542-9547
9.
2004
Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated
mesoderm induction. │ Genes Dev. │ 18 (4),pp.381-386
10.
2002
The metalloprotease Kuzbanian (ADAM10) mediates the
transactivation of EGF receptor by G protein-coupled receptors. │ J Cell Biol. │ 158 (2),pp.221-226
11.
2001
Roles of Meltrin beta/ADAM19 in the processing of neuregulin. │ J Biol Chem. │ 276 (12),pp.9352-9358
12.
1997
TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal
kinase. │ J Biol Chem. │ 272 (13),pp.8141-8144
13.
1996
TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. │ Science. │ 272 (5265),pp.1179-1182
14.
1995
Identification of a member of the MAPKKK family as a potential mediator of TGF-beta
signal transduction. │ Science. │ 270 (5244),pp.2008-2011
15.
1992
Amitogen-activated protein (MAP) kinase activating factor in mammalian mitogen-stimulated cells is homologous to Xenopus M phase MAP kinase activator. │ J Biol Chem. │ 267 (23),pp.16685-16690