Ritsumeikan University Researcher Database
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NEGORO RYOSUKE
Department / Course
College of Pharmaceutical Sciences Department of Pharmacy
Title / Position
Assistant Professor
Papers
1.
2023/07
5-ALA treatment increases intracellular heme levels and enhances CYP3A4 activity in genome-edited Caco-2 cells. │ Biochem. Biophys. Res. Commun. │ 664,pp.94-99 (Co-authored)
2.
2023/07
Defects in early synaptic formation and neuronal function in Prader-Willi syndrome. │ Sci. Rep. │ 13 (1),pp.12053 (Co-authored)
3.
2023/06
Generation of Caco-2 cells with predictable metabolism by CYP3A4, UGT1A1 and CES using the PITCh system. │ Drug Metab. Pharmacokinet. │ 50,pp.100497 (Co-authored)
4.
2023/03
Elucidation of the liver pathophysiology of COVID-19 patients using liver-on-a-chips. │ PNAS Nexus │ 2 (3),pp.029 (Co-authored)
5.
2022/02
Generation of Caco-2 cells stably expressing
CYP3A4·POR·UGT1A1
and
CYP3A4·POR·UGT1A1*6
using a PITCh system. │ Arch. Toxicol. │ 96 (2),pp.499-510 (Co-authored)
6.
2021/08
Usability of Polydimethylsiloxane-Based Microfluidic Devices in Pharmaceutical Research Using Human Hepatocytes. │ ACS. Biomater. Sci. Eng. │ 7 (8),pp.3648-3657 (Co-authored)
7.
2021/04
Asymmetric profiles of infection and innate immunological responses in human iPS cell-derived small intestinal epithelial-like cell monolayers following infection with mammalian reovirus. │ Virus Res. │ 296,pp.198334 (Co-authored)
8.
2021/03
Magnetization of mesenchymal stem cells using magnetic liposomes enhances their retention and immunomodulatory efficacy in mouse inflamed skeletal muscle. │ Int. J. Pharm. │ 596,pp.120298 (Co-authored)
9.
2021/03
Vinblastine treatment enhances the intestinal functions and decreases the undifferentiated cell contamination of human iPS cell-derived intestinal epithelial-like cells. │ Mol. Ther. Methods. Clin. Dev. │ 20,pp.463-472 (Co-authored)
10.
2021/02
Noradrenaline protects neurons against H
2
O
2
-induced death by increasing the supply of glutathione from astrocytes via β
3
-adrenoceptor stimulation. │ J. Neurosci. Res. │ 99 (2),pp.621-637 (Co-authored)
11.
2020/06
Establishment of MDR1-knockout human induced pluripotent stem cell line. │ Drug Metab. Pharmacokinet. │ 35 (3),pp.288-296 (Co-authored)
12.
2020/06
Establishment of SLC15A1/PEPT1-knockout human induced pluripotent stem cell line for intestinal drug absorption studies. │ Mol. Ther. Methods. Clin. Dev. │ 17,pp.49-57 (Co-authored)
13.
2020
Mesenchymal stem cells after the inflammatory response of C2C12 mouse skeletal muscle cells. │ Biol. Pharm. Bull. │ 43 (11),pp.1785-1791 (Co-authored)
14.
2019/06
Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction. │ Cell. Mol. Gastroenterol. Hepatol. │ 8,pp.513-526 (Co-authored)
15.
2018/12
Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies. │ Stem Cell Reports │ 11 (6),pp.1539-1550 (Co-authored)
16.
2016/04
Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells. │ Biochem. Biophys. Res. Commun. │ (472),pp.631-636 (Co-authored)
17.
2015/11
Generation of enterocyte-like cells from human induced pluripotent stem cells for drug absorption and metabolism studies in human small intestine. │ Sci. Rep. │ (5),pp.16479 (Co-authored)