研究者学術情報データベース

ネゴロ　リョウスケ
根来　亮介
NEGORO RYOSUKE

所属薬学部薬学科

職名助教

論文
1.	2024/08	Efficient Proximal Tubule-on-Chip Model from hiPSC-Derived Kidney Organoids for Functional Analysis of Renal Transporters │ iScience │ Online ahead of print. (共著)
2.	2024/07/03	Construction of multilayered small intestine-like tissue by reproducing interstitial flow │ Cell Stem Cell │ Online ahead of print. (共著)
3.	2024/07	Perfluoropolyether-Based Gut-Liver-on-a-Chip for the Evaluation of First-Pass Metabolism and Oral Bioavailability of Drugs │ ACS. Biomater. Sci. Eng. │ 10 (7),4635-4644頁 (共著)
4.	2024	Refining Hepatocyte Models to Capture the Impact of CYP2D6*10 Utilizing a PITCh System │ Biol. Pharm. Bull. │ 47 (8),1422-1428頁 (共著)
5.	2023/07	5-ALA treatment increases intracellular heme levels and enhances CYP3A4 activity in genome-edited Caco-2 cells. │ Biochem. Biophys. Res. Commun. │ 664,94-99頁 (共著)
6.	2023/07	Defects in early synaptic formation and neuronal function in Prader-Willi syndrome. │ Sci. Rep. │ 13 (1),12053 (共著)
7.	2023/06	Generation of Caco-2 cells with predictable metabolism by CYP3A4, UGT1A1 and CES using the PITCh system. │ Drug Metab. Pharmacokinet. │ 50,100497 (共著)
8.	2023/03	Elucidation of the liver pathophysiology of COVID-19 patients using liver-on-a-chips. │ PNAS Nexus │ 2 (3),029 (共著)
9.	2022/05	Generation of HepG2 Cells with High Expression of Multiple Drug-Metabolizing Enzymes for Drug Discovery Research Using a PITCh System. │ Cells │ 11 (10),1677 (共著)
10.	2022/02	Generation of Caco-2 cells stably expressing CYP3A4·POR·UGT1A1 and CYP3A4·POR·UGT1A16* using a PITCh system. │ Arch. Toxicol. │ 96 (2),499-510頁 (共著)
11.	2021/08	Usability of Polydimethylsiloxane-Based Microfluidic Devices in Pharmaceutical Research Using Human Hepatocytes. │ ACS. Biomater. Sci. Eng. │ 7 (8),3648-3657頁 (共著)
12.	2021/04	Asymmetric profiles of infection and innate immunological responses in human iPS cell-derived small intestinal epithelial-like cell monolayers following infection with mammalian reovirus. │ Virus Res. │ 296,198334 (共著)
13.	2021/03	Magnetization of mesenchymal stem cells using magnetic liposomes enhances their retention and immunomodulatory efficacy in mouse inflamed skeletal muscle. │ Int. J. Pharm. │ 596,120298 (共著)
14.	2021/03	Vinblastine treatment enhances the intestinal functions and decreases the undifferentiated cell contamination of human iPS cell-derived intestinal epithelial-like cells. │ Mol. Ther. Methods. Clin. Dev. │ 20,463-472頁 (共著)
15.	2021/02	Noradrenaline protects neurons against H₂O₂-induced death by increasing the supply of glutathione from astrocytes via β₃-adrenoceptor stimulation. │ J. Neurosci. Res. │ 99 (2),621-637頁 (共著)
16.	2020/06	Establishment of MDR1-knockout human induced pluripotent stem cell line. │ Drug Metab. Pharmacokinet. │ 35 (3),288-296 (共著)
17.	2020/06	Establishment of SLC15A1/PEPT1-knockout human induced pluripotent stem cell line for intestinal drug absorption studies. │ Mol. Ther. Methods. Clin. Dev. │ 17,49-57 (共著)
18.	2020	Mesenchymal stem cells after the inflammatory response of C2C12 mouse skeletal muscle cells. │ Biol. Pharm. Bull. │ 43 (11),1785-1791頁 (共著)
19.	2019/06	Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction. │ Cell. Mol. Gastroenterol. Hepatol. │ 8,513-526 (共著)
20.	2018/12	Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies. │ Stem Cell Reports │ 11 (6),1539-1550 (共著)
21.	2016/04	Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells. │ Biochem. Biophys. Res. Commun. │ (472),631-636 (共著)
22.	2015/11	Generation of enterocyte-like cells from human induced pluripotent stem cells for drug absorption and metabolism studies in human small intestine. │ Sci. Rep. │ (5),16479 (共著)